Networked targeting (NT) is a new combat concept and technology with respect to satisfying the Network Central War. According to the character of the networked targeting, the air to air missile launch manner is analyzed and the method of calculating the missile launch acceptability region is given. The one-dimensional golden section is used to search the missile launch acceptability region based on the missile and target moving model. The air to air missile launch acceptability region is calculated in a simulation which combines six typical formations under NT. The launching areas of NT are compared with that of platform targeting, and the variation trend of missile launch acceptability region is summarized.