Numerical simulations of oblique Shock-wave turbulent boundary-layer interaction on flat plate using GAO-YONG compressible turbulent model are presented. Convection terms and diffusion terms are calculated using AUSM scheme and CD (center difference) scheme in the present procedure, respectively. The Runge-Kutta time marching method is employed to solve space discrete control equations. This paper presents three cases with different incident shock angles, which induce attached and separation flows. Compressions between the computation and experiment are carried out including surface pressure distribution, mean velocity profiles, wall skin friction Cf and Stanton number. Good agreements between the calculations and experiment are obtained for the attached flow and incipient separation flow. Meanwhile, GAO-YONG turbulent model can predict distinct separation flow under the intensity interaction at high Mach number.