With the rapid development of science and technology, the traditional manmachine interface of antiaircraft antimissile equipment display and control platform is unable to adapt to the increase of information volume and time pressure in the course of combat. In order to improve the operation performance and reduce the cognitive load of operators, a design concept of “humancentered” should be emphasized more in the process of interface design, and a concept of intuitive interaction design should be integrated into the design process. Firstly, the manmachine interface of each display and control station in the charge cabin is analyzed, the existing problems are pointed out, the layout principle by using fuzzy analytic hierarchy process is quantified, and a layout optimization model is established. Secondly, in consideration of the fuzziness of the interface evaluation index, a multiattribute fuzzy comprehensive evaluation method is proposed to evaluate the optimization scheme. The optimization scheme and the evaluation method are valid.