Aimed at the advantages that UAV ammunition damage to the airport runway is of zero damage and zero death, this paper proposes a kind of damaging and combating model on penetration and explosion of airport runway in the UAV small blockade ammunition based on Autodyn. A huge losses of aircraft and personnel damaging airport runway is avoided. By depending on the Design-Model tool, this paper builds up a 10:1 model of BM100 light anti-runway bomb, and performs a simulation under conditions of Autodyn environments. The cycle process of penetration and explosion and key Gauges point waveform chart and damaging cloud chart are obtained for 10:1 model. The result shows that BM100 read depth and radius of blasting pit are 500mm and 400mm based on geometric similarity model. The hollow phenomenon is appeared in the lower part of blasting pit. this caused great difficulties to repair the airport and more difficult to repair than blasting pit.