Based on the characteristics of amplitude and phase between the main and auxiliary channels, the effects of antenna polarization on Adaptive Side-lobe Canceller under arbitrary polarization interference are analyzed. The polarization difference between the antennas will finally result in the amplitude and phase errors, the most serious errors occur with cross-polarization interference; the cancellation ratio is also the worst. For good performance of Adaptive Side-lobe Canceller, the antenna polarization performance must be designed well besides the channel amplitude and phase.