Using RF magnetron sputtering method, 300nm La2/3-Pb1/3-MnO3 thin film has been epitaxially grown on (100) LaA103 single - crystal substrates. The structure and the magneto - electrical properties of the thin film are investigated using X ray diffractometer, super-conducting quantum interference device and DC four-probe method. The results exhibit that the thin film with (100) preferred orientation is of a pseudo - cubic perovskite structure and has the good single crystalline. When the Curie temperature is at 335K, nearby the Curie temperature, the magneto-electric properties indicate a transition from ferromagnetic to paramagnetic and exhibit a characteristic of spin glass state, which is due to strain effects. The magnetic rules of paramagnetic state and spin glass state as well as ferromagnetic state are illustrated. The electrical property indicates that the thin film has quite a distinctive magneto-resistance effect which is 23.4% nearby the Curie temperature when the magnetic field is 1T.